DEVELOPMENT TREND OF GROUP VOLUNTARY BLOOD DONATION IN SHANDONG FROM 2012 TO 2020



Glycemic variability and diabetic cardiac autonomic neuropathy

Cardiac autonomic neuropathy (CAN) is closely associated with an approximately five-fold increase in the risk of cardiovascular mortality in patients with diabetes mellitus (DM).Impaired autonomic function of the cardiovascular system in DM, which leads to the development of CAN, can be accompanied by coronary artery ischemia, heart rhythm disturba

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Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction

Abstract Background Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein.For enzymatic proteins, the structure and chemistry of the catalytic binding site residues can be loosely defined as a substructure of the protein.Comparative analysis of drug-receptor substructure

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